Pub. Date : 2008 Jan
PMID : 18054955
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Caveolin-3 expression and caveolae are required for isoflurane-induced cardiac protection from hypoxia and ischemia/reperfusion injury. | Isoflurane | caveolin 3 | Mus musculus |
2 | Isoflurane-induced cardiac protection was abolished in Cav-3(-/-) mice (infarct size: 53.4%+/-6.1% vs. 53.2%+/-3.5%, P<0.01; troponin: 102.1+/-22.3 vs. 105.9+/-8.2 ng/ml, P<0.01). | Isoflurane | caveolin 3 | Mus musculus |
3 | Isoflurane-induced cardiac protection is thus dependent on the presence of caveolae and the expression of caveolin-3. | Isoflurane | caveolin 3 | Mus musculus |