Title : Caveolin-3 expression and caveolae are required for isoflurane-induced cardiac protection from hypoxia and ischemia/reperfusion injury.

Pub. Date : 2008 Jan

PMID : 18054955






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Caveolin-3 expression and caveolae are required for isoflurane-induced cardiac protection from hypoxia and ischemia/reperfusion injury. Isoflurane caveolin 3 Mus musculus
2 Isoflurane-induced cardiac protection was abolished in Cav-3(-/-) mice (infarct size: 53.4%+/-6.1% vs. 53.2%+/-3.5%, P<0.01; troponin: 102.1+/-22.3 vs. 105.9+/-8.2 ng/ml, P<0.01). Isoflurane caveolin 3 Mus musculus
3 Isoflurane-induced cardiac protection is thus dependent on the presence of caveolae and the expression of caveolin-3. Isoflurane caveolin 3 Mus musculus