Title : Secretory signal sequence non-optimal codons are required for expression and export of beta-lactamase.

Pub. Date : 2008 Feb 1

PMID : 18053805






1 Functional Relationships(s)
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1 The difference in ampicillin resistance was reduced at 28 degrees C compared to expression at 37 degrees C, suggesting that the optimised bla allele is misfolded and degraded by heat-shock regulated proteases. Ampicillin beta-lactamase Escherichia coli