Pub. Date : 2008 Apr
PMID : 18048066
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hypoxanthine uptake and release by equilibrative nucleoside transporter 2 (ENT2) of rat microvascular endothelial cells. | Hypoxanthine | equilibrative nucleoside transporter 2 | Rattus norvegicus |
| 2 | Hypoxanthine uptake and release by equilibrative nucleoside transporter 2 (ENT2) of rat microvascular endothelial cells. | Hypoxanthine | equilibrative nucleoside transporter 2 | Rattus norvegicus |
| 3 | The equilibrative nucleoside transporter, ENT2, mediates the transfer of hypoxanthine into cells. | Hypoxanthine | equilibrative nucleoside transporter 2 | Rattus norvegicus |
| 4 | We hypothesize that ENT2 also mediates the cellular release of hypoxanthine, which would limit the amount of intracellular hypoxanthine available for xanthine oxidase-mediated ROS production. | Hypoxanthine | equilibrative nucleoside transporter 2 | Rattus norvegicus |
| 5 | We hypothesize that ENT2 also mediates the cellular release of hypoxanthine, which would limit the amount of intracellular hypoxanthine available for xanthine oxidase-mediated ROS production. | Hypoxanthine | equilibrative nucleoside transporter 2 | Rattus norvegicus |
| 6 | Thus, ENT2 mediates both the influx and efflux of hypoxanthine. | Hypoxanthine | equilibrative nucleoside transporter 2 | Rattus norvegicus |
| 7 | Inhibition of ENT2 in MVECs might be expected to increase the amount of intracellular hypoxanthine available for metabolism by xanthine oxidase and enhance the intracellular production of ROS. | Hypoxanthine | equilibrative nucleoside transporter 2 | Rattus norvegicus |