Title : Nicotinic acid (niacin) receptor agonists: will they be useful therapeutic agents?

Pub. Date : 2007 Dec 3

PMID : 18047854






3 Functional Relationships(s)
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1 Kinetic and in vitro studies indicate that niacin retards the hepatic catabolism of apoA-I but not liver scavenger receptor B1-mediated cholesterol esters, suggesting that niacin inhibits hepatic holoparticle HDL removal. Niacin apolipoprotein A1 Homo sapiens
2 Kinetic and in vitro studies indicate that niacin retards the hepatic catabolism of apoA-I but not liver scavenger receptor B1-mediated cholesterol esters, suggesting that niacin inhibits hepatic holoparticle HDL removal. Niacin apolipoprotein A1 Homo sapiens
3 Indeed, recent preliminary evidence suggests that niacin decreases surface expression of hepatic beta-chain of adenosine triphosphate synthase, which has been implicated in apoA-I/HDL holoparticle catabolism. Niacin apolipoprotein A1 Homo sapiens