Title : In vivo regulation of phenylalanine hydroxylation to tyrosine, studied using enrichment in apoB-100.

Pub. Date : 2008 Feb

PMID : 18042668






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1 A new and more sensitive method to measure label enrichment in proteins using isotope ratio mass spectrometry demonstrated that phenylalanine hydroxylation measured in apoB-100 decreased linearly in response to increasing tyrosine intake and reached a break point at 6.8 mg.kg(-1).day(-1). Tyrosine apolipoprotein B Homo sapiens