Title : [Relationship between autoantibodies and HLA-DQ genotypes in patients with type 1 diabetes mellitus].

Pub. Date : 2007 Sep 11

PMID : 18036312






5 Functional Relationships(s)
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1 The GADA positivity rate of the T1DM patients with DQA1*0102-DQB1 *0602 haplotype was 16.7%, significantly lower than those patients without DQA1*0102-DQB1 *0602 haplotype (45.9%, P < 0.05). gada major histocompatibility complex, class II, DQ alpha 1 Homo sapiens
2 The GADA positivity rate of the T1DM patients with DQA1*0102-DQB1 *0602 haplotype was 16.7%, significantly lower than those patients without DQA1*0102-DQB1 *0602 haplotype (45.9%, P < 0.05). gada major histocompatibility complex, class II, DQ alpha 1 Homo sapiens
3 CONCLUSION: GADA is associated with HLA-DQA1*05-DQB1*0201 and DQA1*03-DQB1*0401 haplotypes, and IA-2A is associated with DQA1*03-DQB1 *0303 haplotype. gada major histocompatibility complex, class II, DQ alpha 1 Homo sapiens
4 CONCLUSION: GADA is associated with HLA-DQA1*05-DQB1*0201 and DQA1*03-DQB1*0401 haplotypes, and IA-2A is associated with DQA1*03-DQB1 *0303 haplotype. gada major histocompatibility complex, class II, DQ alpha 1 Homo sapiens
5 CONCLUSION: GADA is associated with HLA-DQA1*05-DQB1*0201 and DQA1*03-DQB1*0401 haplotypes, and IA-2A is associated with DQA1*03-DQB1 *0303 haplotype. gada major histocompatibility complex, class II, DQ alpha 1 Homo sapiens