Pub. Date : 2008 Feb
PMID : 17998297
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, we found that UGT1A1-catalyzed estradiol 3-O-glucuronide formation and UGT1A4-catalyzed imipramine N-glucuronide formation in human liver microsomes were prominently decreased in the presence of 1-naphthol, but those by recombinant human UGT1A1 and UGT1A4, respectively, were not. | 1-naphthol | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
| 2 | Interestingly, when recombinant UGT1A6 was added in the reaction mixture, these activities by recombinant UGT1A1 and UGT1A4 were diminished in the presence of 1-naphthol. | 1-naphthol | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |