Title : New method for chloroamidation of olefins. Application in the synthesis of N-glycopeptides and anticancer agents.

Pub. Date : 2007 Dec 6

PMID : 17994754






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1 The acetamido sugar derivatives and free amines were found to be promising anticancer agents against the U-87 malignant glyoma (a brain tumor) cell line with IC-50=1 nm-22 microM, and they were found to be far less cytotoxic against a normal human embryonic kidney cell line. free small nucleolar RNA, C/D box 87 Homo sapiens