Title : New targets and emerging therapies for reducing LDL cholesterol.

Pub. Date : 2007 Dec

PMID : 17993811






1 Functional Relationships(s)
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Protein Name
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1 Increases in LDL receptor-mediated cholesterol clearance occur when hepatic cholesterol stores are reduced secondary to inhibition of squalene synthase or LDL receptor degradation is disrupted by reduced activity of proprotein convertase subtilisin kexin type 9. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens