Pub. Date : 2008 Feb
PMID : 17993510
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The resulting hCNT3(C602R) protein has the same selectivity and affinity for natural nucleosides and nucleoside-derived drugs as hCNT3 but much lower concentrative capacity. | Nucleosides | solute carrier family 28 member 3 | Homo sapiens |
| 2 | The resulting hCNT3(C602R) protein has the same selectivity and affinity for natural nucleosides and nucleoside-derived drugs as hCNT3 but much lower concentrative capacity. | Nucleosides | solute carrier family 28 member 3 | Homo sapiens |
| 3 | The sodium activation kinetic analysis of both transporters revealed a variation in the affinity for sodium and a shift in the Hill coefficient that could be consistent with a stoichiometry of 2:1 and 1:1 sodium/nucleoside, for hCNT3 and hCNT3(C602R), respectively. | Nucleosides | solute carrier family 28 member 3 | Homo sapiens |
| 4 | The sodium activation kinetic analysis of both transporters revealed a variation in the affinity for sodium and a shift in the Hill coefficient that could be consistent with a stoichiometry of 2:1 and 1:1 sodium/nucleoside, for hCNT3 and hCNT3(C602R), respectively. | Nucleosides | solute carrier family 28 member 3 | Homo sapiens |
| 5 | Individuals with the hCNT3(C602R) variant might show a lower nucleoside and nucleoside analog concentrative capacity, which could be clinically relevant. | Nucleosides | solute carrier family 28 member 3 | Homo sapiens |
| 6 | Individuals with the hCNT3(C602R) variant might show a lower nucleoside and nucleoside analog concentrative capacity, which could be clinically relevant. | Nucleosides | solute carrier family 28 member 3 | Homo sapiens |