Title : GSK-3beta inhibition enhances sorafenib-induced apoptosis in melanoma cell lines.

Pub. Date : 2008 Jan 11

PMID : 17991738






2 Functional Relationships(s)
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1 Pharmacologic inhibition and/or down-modulation of the kinase enhances sorafenib-induced apoptosis as determined by propidium iodide staining and by assessing the mitochondrial release of apoptosis-inducing factor and Smac/DIABLO. Sorafenib diablo IAP-binding mitochondrial protein Homo sapiens
2 Pharmacologic inhibition and/or down-modulation of the kinase enhances sorafenib-induced apoptosis as determined by propidium iodide staining and by assessing the mitochondrial release of apoptosis-inducing factor and Smac/DIABLO. Sorafenib diablo IAP-binding mitochondrial protein Homo sapiens