Pub. Date : 2008 Jan 11
PMID : 17989073
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Unexpectedly, we encountered NPC1 in a search for a membrane protein that binds 25-hydroxycholesterol (25-HC) and other oxysterols. | Oxysterols | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 2 | We prepared recombinant human NPC1 and confirmed its ability to bind oxysterols, including those with a hydroxyl group on the 24, 25, or 27 positions. | Oxysterols | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 3 | The availability of assays to measure NPC1 binding in vitro may further the understanding of ways in which oxysterols regulate intracellular lipid transport. | Oxysterols | NPC intracellular cholesterol transporter 1 | Homo sapiens |