Pub. Date : 2008 Feb
PMID : 17965457
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
| 2 | Because two of these amino acids (Cys and His) are members of the catalytic triad of human BAT, it was proposed that 4HNE would cause inactivation of this enzyme. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
| 3 | To establish the sites of 4HNE"s reaction with BAT, peptides from proteolysis of 4HNE-treated, recombinant human BAT were analyzed by peptide mass fingerprinting and by electrospray ionization-tandem mass spectrometry using a hybrid linear ion trap Fourier transform-ion cyclotron resonance mass spectrometer. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
| 4 | To establish the sites of 4HNE"s reaction with BAT, peptides from proteolysis of 4HNE-treated, recombinant human BAT were analyzed by peptide mass fingerprinting and by electrospray ionization-tandem mass spectrometry using a hybrid linear ion trap Fourier transform-ion cyclotron resonance mass spectrometer. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
| 5 | To establish the sites of 4HNE"s reaction with BAT, peptides from proteolysis of 4HNE-treated, recombinant human BAT were analyzed by peptide mass fingerprinting and by electrospray ionization-tandem mass spectrometry using a hybrid linear ion trap Fourier transform-ion cyclotron resonance mass spectrometer. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
| 6 | To establish the sites of 4HNE"s reaction with BAT, peptides from proteolysis of 4HNE-treated, recombinant human BAT were analyzed by peptide mass fingerprinting and by electrospray ionization-tandem mass spectrometry using a hybrid linear ion trap Fourier transform-ion cyclotron resonance mass spectrometer. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |