Pub. Date : 2008 Jan 1
PMID : 17962328
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Heteromeric NMDARs are composed of coagonist glycine-binding NR1 subunits and glutamate-binding NR2 subunits. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 2 | This heterogeneity is specified by the particular NR2 subunit within the NMDAR complex since the glycine-binding NR1 subunit is common to all NMDARs investigated. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 3 | We conclude that the variation in glycine potency is caused by interactions between the NR1 and NR2 ligand-binding domains that occur following agonist binding and which may be involved in the initial conformation changes that determine channel gating. | Glycine | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |