Title : [Mechanisms underlying the effect of arsenic trioxide on proliferation inhibition and apoptosis induction in myeloma cell line u266].

Pub. Date : 2007 Oct

PMID : 17956674






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 After treating U266 cells with 2 micromol/L As2O3 at different time points, a time-dependent reduction of procaspase-3, hTERT mRNA and protein was found without any change of bcl-2 expression. Arsenic Trioxide telomerase reverse transcriptase Homo sapiens
2 These findings suggest that the reduction of hTERT plays a critical role in the apoptosis of U266 cells induced by As2O3. Arsenic Trioxide telomerase reverse transcriptase Homo sapiens