Pub. Date : 2007 Dec 1
PMID : 17935989
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | These compounds significantly sensitize tumor cells to the DNA-damaging antitumor agent doxorubicin in a cell-based assay and efficiently abrogate the doxorubicin-induced G2/M and camptothecin-induced S checkpoints, indicating that the potent biological activities of these compounds are mechanism-based through Chk1 inhibition. | Camptothecin | checkpoint kinase 1 | Homo sapiens |