Pub. Date : 2007 Nov 7
PMID : 17935701
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Distributions of glucuronyltransferases, GlcAT-P and GlcAT-S, and their target substrate, the HNK-1 carbohydrate epitope in the adult mouse brain with or without a targeted deletion of the GlcAT-P gene. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
2 | It is known that the HNK-1 carbohydrate is synthesized through two key enzymes, glucuronyltransferases (GlcAT-P and GlcAT-S). | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
3 | It was shown histologically that the localization of HNK-1 carbohydrate paralleled the pattern of expression of GlcAT transcripts in the brain. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
4 | Additionally, the localization of HNK-1 carbohydrate was restricted partially in the brain of GlcAT-P-deficient mice, while the HNK-1 carbohydrate was widely distributed over most of the brain of wild-type mice. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
5 | Additionally, the localization of HNK-1 carbohydrate was restricted partially in the brain of GlcAT-P-deficient mice, while the HNK-1 carbohydrate was widely distributed over most of the brain of wild-type mice. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
6 | The present study provides a new framework for understanding the network constructed by the HNK-1 carbohydrate in the central nervous system. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |