Title : Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages.

Pub. Date : 2007 Aug 31

PMID : 17934341






2 Functional Relationships(s)
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1 Genistein, a protein tyrosine kinase (PTK) inhibitor, and PD153035, an EGFR inhibitor, also blocked the increase of TNF-alpha expression by TCDD, indicating the role of EGFR in TCDD-induced TNF-alpha expression. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline tumor necrosis factor Homo sapiens
2 Genistein, a protein tyrosine kinase (PTK) inhibitor, and PD153035, an EGFR inhibitor, also blocked the increase of TNF-alpha expression by TCDD, indicating the role of EGFR in TCDD-induced TNF-alpha expression. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline tumor necrosis factor Homo sapiens