Title : Catalysis of zinc transfer by D-penicillamine to secondary chelators.

Pub. Date : 2007 Nov 1

PMID : 17918925






1 Functional Relationships(s)
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1 The antiarthritis drug D-penicillamine (D-PEN) catalyzes zinc(II) transfer from carboxypeptidase A to chelators such as thionein and EDTA at a rate constant up to 400-fold faster than the uncatalyzed release. Penicillamine proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens