Pub. Date : 2007 Nov
PMID : 17916406
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our results demonstrate that the only RA isomers detected in RALDH1-expressing or non-expressing cells corresponded to the same steric conformation as the supplied retinoids, indicating a lack of measurable 9-cis/all-trans retinoid-isomerizing activity. | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |
| 2 | Finally, HeLa cells transfected with RALDH1 derivatives that were retinal isomer-selective in vitro produced only the corresponding RA isomers, establishing these enzymes as useful tools to assess the respective roles of the two RA isomers in vivo. | Tretinoin | aldehyde dehydrogenase 1 family member A1 | Homo sapiens |