Title : Estradiol favors the formation of eicosapentaenoic acid (20:5n-3) and n-3 docosapentaenoic acid (22:5n-3) from alpha-linolenic acid (18:3n-3) in SH-SY5Y neuroblastoma cells.

Pub. Date : 2008 Jan

PMID : 17912567






1 Functional Relationships(s)
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1 E2 significantly favored EPA and DPA production in cells grown for 72 h. Enhanced synthesis of ALA-elongation products in neuroblastoma cells treated with E2 supports the hypothesis that neurosteroids could modulate the metabolism of PUFA. alpha-Linolenic Acid pumilio RNA binding family member 3 Homo sapiens