Title : Dynamic changes of XPA, XPC, XPF, XPG and ERCC1 protein expression and their correlations with levels of DNA damage in human bronchial epithelia cells exposed to benzo[a]pyrene.

Pub. Date : 2007 Nov 1

PMID : 17900831






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Dynamic changes of XPA, XPC, XPF, XPG and ERCC1 protein expression and their correlations with levels of DNA damage in human bronchial epithelia cells exposed to benzo[a]pyrene. Benzo(a)pyrene ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
2 ERCC1 expression increased by 2.4-, 4.2- and 19.3-fold for exposure to 2, 8 and 16microM BaP, respectively, compared with control group. Benzo(a)pyrene ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
3 Moreover, levels of ERCC1 in cells exposed 16microM BaP significantly higher than those in 2 and 8microM BaP from 2nd to 48th hours. Benzo(a)pyrene ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
4 Moreover, levels of ERCC1 in cells exposed 16microM BaP significantly higher than those in 2 and 8microM BaP from 2nd to 48th hours. Benzo(a)pyrene ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
5 In addition, there was a significant positive correlation between Olive tail moments and relative ratios of ERCC1 in cells exposed to BaP. Benzo(a)pyrene ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens