Title : Inhibition of HMG-CoA reductase in mononuclear cells during gemfibrozil treatment.

Pub. Date : 1991 Dec

PMID : 1789808






1 Functional Relationships(s)
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1 It is suggested that the HMG-CoA reductase inhibition observed in mononuclear cells during gemfibrozil treatment is due to changes in LDL structure affecting LDL receptor binding rather than direct effects of the drug on cellular cholesterol metabolism. Gemfibrozil low density lipoprotein receptor Homo sapiens