Title : Determination of hydroxycamptothecin affinities to albumin and membranes by steady-state fluorescence anisotropy measurements.

Pub. Date : 2007 Jul

PMID : 17896945






1 Functional Relationships(s)
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1 A serious limitation to the clinical application of CPT is the strong affinity of its carboxylate form to human serum albumin (HSA) which destabilizes its active lactone form. Camptothecin albumin Homo sapiens