Title : Targeting NOX, INOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals.

Pub. Date : 2007 Dec 1

PMID : 17893865






1 Functional Relationships(s)
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1 For example, 1"-acetoxychavicol acetate, which occurs in the rhizomes of the subtropical Zingiberaceae plant, has been shown to attenuate NOX-derived superoxide generation in macrophages, as well as lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production through the suppression of iNOS and COX-2 synthesis, respectively. Superoxides mitochondrially encoded cytochrome c oxidase II Homo sapiens