Pub. Date : 2007 Nov 23
PMID : 17893149
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | KEG1/YFR042w encodes a novel Kre6-binding endoplasmic reticulum membrane protein responsible for beta-1,6-glucan synthesis in Saccharomyces cerevisiae. | beta-1,6-glucan | Keg1p | Saccharomyces cerevisiae S288C |
2 | Immunoprecipitation from the Triton X-100-solubilized cell lysate revealed that Keg1 binds to Kre6, which has been known to participate in beta-1,6-glucan synthesis. | beta-1,6-glucan | Keg1p | Saccharomyces cerevisiae S288C |
3 | The keg1-1 mutant cells showed a common phenotype with Deltakre6 mutant including hypersensitivity to Calcofluor white, reduced sensitivity to the K1 killer toxin, and reduced content of beta-1,6-glucan in the cell wall. | beta-1,6-glucan | Keg1p | Saccharomyces cerevisiae S288C |
4 | These results suggest that Keg1 and Kre6 have a cooperative role in beta-1,6-glucan synthesis in S. cerevisiae. | beta-1,6-glucan | Keg1p | Saccharomyces cerevisiae S288C |