Title : Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice.

Pub. Date : 2008 Apr

PMID : 17883406






2 Functional Relationships(s)
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1 The products of Golgi UDP-GlcNAc:N-acetylglucosaminyltransferases (encoded by Mgat1, Mgat2, Mgat4 and Mgat5) act sequentially to generate the GlcNAc-branched complex-type N-glycans on glycoprotein receptors. n-glycans mannoside acetylglucosaminyltransferase 5 Mus musculus
2 Our results indicate that Mgat5 modification of complex-type N-glycans on CNS glycoproteins is involved in the regulation of depression-like behavior. n-glycans mannoside acetylglucosaminyltransferase 5 Mus musculus