Title : 17alpha-estradiol inhibits LAPC-4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals.

Pub. Date : 2007 Dec 1

PMID : 17879940






2 Functional Relationships(s)
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Protein Name
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1 The inhibition of cell proliferation was associated with a blockade of DHT-induced cyclin A and cyclin D1 expression by alphaE2 and betaE2. Dihydrotestosterone cyclin D1 Homo sapiens
2 CONCLUSION: alphaE2 is an effective agent for inhibition of DHT-induced PSA, cyclin A, cyclin D1 gene expression, and cell proliferation in LAPC-4 cells, and tumor growth in LAPC-4 xenograft mice. Dihydrotestosterone cyclin D1 Homo sapiens