Title : Ethanol inhibits methionine adenosyltransferase II activity and S-adenosylmethionine biosynthesis and enhances caspase-3-dependent cell death in T lymphocytes: relevance to alcohol-induced immunosuppression.

Pub. Date : 2008 Jun

PMID : 17869084






1 Functional Relationships(s)
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1 It has been demonstrated that the formation of S-adenosylmethionine (SAMe) catalyzed by methionine adenosyltransferase (MAT) II is essential for CD4(+) T-cell activation and proliferation. S-Adenosylmethionine methionine adenosyltransferase 2A Homo sapiens