Pub. Date : 2007 Nov
PMID : 17846144
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The MICs of ciprofloxacin and levofloxacin for Spn-058 were both 1 microg/ml when susceptibility testing was conducted with each antibiotic alone and with each antibiotic in the presence of reserpine. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |
| 2 | For Spn-058, simulated regimens of ciprofloxacin at 750 mg every 12 h or levofloxacin at 500 mg QD were associated with the emergence of fluoroquinolone resistance. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |
| 3 | However, the use of ciprofloxacin at 750 mg every 12 h and levofloxacin at 500 mg QD in combination with reserpine rapidly killed Spn-058 and prevented the emergence of resistance. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |
| 4 | For Spn-RC2, levofloxacin at 500 mg QD was associated with the emergence of resistance, but again, the resistance was prevented when this levofloxacin regimen was combined with reserpine. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |
| 5 | Levofloxacin at 750 mg QD, with and without reserpine, effectively eradicated Spn-058 and Spn-RC2 without selecting for fluoroquinolone resistance. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |
| 6 | Levofloxacin at 750 mg QD, with and without reserpine, effectively eradicated Spn-058 and Spn-RC2 without selecting for fluoroquinolone resistance. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |
| 7 | These studies also showed that ciprofloxacin was a better inducer of EP expression than levofloxacin in both Spn-058 and Spn-RC2. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |
| 8 | These studies also showed that ciprofloxacin was a better inducer of EP expression than levofloxacin in both Spn-058 and Spn-RC2. | Levofloxacin | DEAF1 transcription factor | Homo sapiens |