Pub. Date : 2007
PMID : 17827975
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The antifungal activity of RsAFP2, a plant defensin from raphanus sativus, involves the induction of reactive oxygen species in Candida albicans. | Reactive Oxygen Species | defensin-like protein 2 | Raphanus sativus |
| 2 | We show that RsAFP2 induces reactive oxygen species (ROS) in Candida albicans wild type in a dose-dependent manner, but not at all in an RsAFP2-resistant DeltagcsC. | Reactive Oxygen Species | defensin-like protein 2 | Raphanus sativus |
| 3 | We show that RsAFP2 induces reactive oxygen species (ROS) in Candida albicans wild type in a dose-dependent manner, but not at all in an RsAFP2-resistant DeltagcsC. | Reactive Oxygen Species | defensin-like protein 2 | Raphanus sativus |
| 4 | These findings indicate that upstream binding of RsAFP2 to GlcCer is needed for ROS production leading to yeast cell death. | Reactive Oxygen Species | defensin-like protein 2 | Raphanus sativus |
| 5 | Moreover, the antioxidant ascorbic acid blocks RsAFP2-induced ROS generation, as well as RsAFP2 antifungal activity. | Reactive Oxygen Species | defensin-like protein 2 | Raphanus sativus |