Title : Tumor-associated Tn-MUC1 glycoform is internalized through the macrophage galactose-type C-type lectin and delivered to the HLA class I and II compartments in dendritic cells.

Pub. Date : 2007 Sep 1

PMID : 17804752






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Glycopeptides corresponding to three tandem repeats of MUC1, enzymatically glycosylated with 9 or 15 mol of GalNAc, were shown to specifically bind and to be internalized by immature monocyte-derived DCs (iDCs). N-acetylgalactosaminuronic acid mucin 1, cell surface associated Homo sapiens
2 Binding required calcium and the GalNAc residue and was competed out by GalNAc polymer and Tn-MUC1 or Tn-MUC2 glycopeptides. N-acetylgalactosaminuronic acid mucin 1, cell surface associated Homo sapiens