Title : Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells.

Pub. Date : 2007 Sep 15

PMID : 17785809






3 Functional Relationships(s)
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1 We found that the major vitamin A metabolite all-trans-retinoic acid induces histone acetylation at the FoxP3 gene promoter and expression of the FoxP3 protein in CD4+ T cells. Tretinoin forkhead box P3 Mus musculus
2 We found that the major vitamin A metabolite all-trans-retinoic acid induces histone acetylation at the FoxP3 gene promoter and expression of the FoxP3 protein in CD4+ T cells. Tretinoin forkhead box P3 Mus musculus
3 Retinoic acid can promote TGF-beta1-dependent generation of FoxP3+ regulatory T cells but decrease the TGF-beta1- and IL-6-dependent generation of inflammatory Th17 cells in mouse T cells. Tretinoin forkhead box P3 Mus musculus