Title : Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells.

Pub. Date : 2007 Dec

PMID : 17761766






1 Functional Relationships(s)
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1 We previously found that Janus kinase 2 (JAK2)-deficient GHR-expressing cells have a greater precursor/mature GHR ratio, exhibit diminished inducible metalloproteolysis, and have a cytoplasmic domain-containing GHR fragment called the basal remnant (by virtue of comigration on SDS-PAGE with the inducible, metalloprotease-generated remnant). Sodium Dodecyl Sulfate growth hormone receptor Homo sapiens