Title : Serum prolactin levels, plasma risperidone levels, polymorphism of cytochrome P450 2D6 and clinical response in patients with schizophrenia.

Pub. Date : 2007 Nov

PMID : 17715206






1 Functional Relationships(s)
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1 The object of this study is to assess 1) the relationship between plasma antipsychotic drug concentration, serum prolactin levels and the clinical efficacy of risperidone, 2) the relationship between the CYP2D6 polymorphisms and metabolizing of risperidone and 3) the role of 9-hydroxyrisperidone in elevating prolactin levels. Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens