Title : A methionine-free diet associated with nitrosourea treatment down-regulates methylguanine-DNA methyl transferase activity in patients with metastatic cancer.

Pub. Date : 2007 Jul-Aug

PMID : 17695447






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This potentiating effect may be due to tumor cell sensitization to chloroethylnitrosoureas through their MET dependency and the down-regulation of O6- methylguanine-DNA methyltransferase (MGMT). 1-(2-chloroethyl)-1-nitrosourea O-6-methylguanine-DNA methyltransferase Homo sapiens
2 This potentiating effect may be due to tumor cell sensitization to chloroethylnitrosoureas through their MET dependency and the down-regulation of O6- methylguanine-DNA methyltransferase (MGMT). 1-(2-chloroethyl)-1-nitrosourea O-6-methylguanine-DNA methyltransferase Homo sapiens