Pub. Date : 2007 Sep 7
PMID : 17690258
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We determined the crystal structure at 2.9 angstroms of the bacterial leucine transporter (LeuT), a homolog of SERT, NET, and DAT, in complex with leucine and the antidepressant desipramine. | Desipramine | solute carrier family 6 member 3 | Homo sapiens |
| 2 | Mutagenesis experiments on human SERT and DAT indicate that both the desipramine-binding site and its inhibition mechanism are probably conserved in the human neurotransmitter transporters. | Desipramine | solute carrier family 6 member 3 | Homo sapiens |