Title : Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways.

Pub. Date : 2007 Nov

PMID : 17673311






1 Functional Relationships(s)
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1 P38-MAPK-specific inhibitors attenuate the As(2)O(3) plus TNFalpha-provoked activation of caspase-8/Bid, Bax translocation, cytochrome c release, and apoptosis induction. Arsenic Trioxide BCL2 associated X, apoptosis regulator Homo sapiens