Title : CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Pub. Date : 2007 Nov

PMID : 17671098






3 Functional Relationships(s)
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1 Furthermore, the addition of 8-methoxypsoralen, a CYP2A inhibitor, led to greater inhibition of NNK metabolic activation in microsomes containing relatively high levels of CYP2A13 than in samples containing no detectable CYP2A13. Methoxsalen cytochrome P450 family 2 subfamily A member 13 Homo sapiens
2 Furthermore, the addition of 8-methoxypsoralen, a CYP2A inhibitor, led to greater inhibition of NNK metabolic activation in microsomes containing relatively high levels of CYP2A13 than in samples containing no detectable CYP2A13. Methoxsalen cytochrome P450 family 2 subfamily A member 13 Homo sapiens
3 Furthermore, the addition of 8-methoxypsoralen, a CYP2A inhibitor, led to greater inhibition of NNK metabolic activation in microsomes containing relatively high levels of CYP2A13 than in samples containing no detectable CYP2A13. Methoxsalen cytochrome P450 family 2 subfamily A member 13 Homo sapiens