Title : Sulfiredoxin, the cysteine sulfinic acid reductase specific to 2-Cys peroxiredoxin: its discovery, mechanism of action, and biological significance.

Pub. Date : 2007 Aug

PMID : 17653208






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Reduction of sulfinic Prx enzymes, the first known biological example of such a reaction, is catalyzed by sulfiredoxin (Srx) in the presence of ATP. Adenosine Triphosphate sulfiredoxin 1 Homo sapiens
2 Reduction of sulfinic Prx enzymes, the first known biological example of such a reaction, is catalyzed by sulfiredoxin (Srx) in the presence of ATP. Adenosine Triphosphate sulfiredoxin 1 Homo sapiens
3 Srx specifically binds to 2-Cys Prx enzymes by recognizing several critical surface-exposed residues of the Prxs, and transfer the gamma-phosphate of ATP to their sulfinic moiety, using its conserved cysteine as the phosphate carrier. Adenosine Triphosphate sulfiredoxin 1 Homo sapiens