Title : Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway.

Pub. Date : 2007 Aug 31

PMID : 17631493






1 Functional Relationships(s)
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1 Formation of the last ring via C-1/C-18 aldol condensation does not require a dedicated fourth-ring cyclase, in contrast to the biosynthetic mechanism of other tetracyclic aromatic polyketides, such as daunorubicin and tetracenomycin. Daunorubicin heterogeneous nuclear ribonucleoprotein C Homo sapiens