Title : PTEN expression contributes to the regulation of muscle protein degradation in diabetes.

Pub. Date : 2007 Oct

PMID : 17623817






1 Functional Relationships(s)
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1 RESEARCH DESIGN AND METHODS: We evaluated the expression and activity of PTEN, the phosphatase converting PIP(3) to inactive phosphatidylinositol 4,5-bisphosphate, and studied how PTEN influences muscle protein in diabetic wild-type mice and in mice with partial deficiency of PTEN(+/-). pip(3) phosphatase and tensin homolog Mus musculus