Title : TGF-beta1 release by volatile anesthetics mediates protection against renal proximal tubule cell necrosis.

Pub. Date : 2007

PMID : 17622749






1 Functional Relationships(s)
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1 METHODS AND RESULTS: In human proximal tubule (HK-2) cell culture, 16-hour exposure to volatile anesthetics (isoflurane, halothane, sevoflurane) caused membrane externalization of PS detected by positive annexin-V staining and increased the release of TGF-beta1 into the cell culture media. Halothane transforming growth factor beta 1 Homo sapiens