Title : [Research and development of pravastatin].

Pub. Date : 1991 Sep

PMID : 1762049






1 Functional Relationships(s)
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1 The attempts to find a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase which catalyzes the rate limiting step of cholesterol biosynthesis were started from 1971. Cholesterol 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oryctolagus cuniculus