Title : Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy.

Pub. Date : 2007 Jul 24

PMID : 17618624






3 Functional Relationships(s)
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Protein Name
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1 We identified the human WIPI protein family of PI(3)P-binding factors and showed that WIPI-1 (Atg18) is linked to autophagy in human cells. 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) WD repeat domain, phosphoinositide interacting 1 Homo sapiens
2 We identified the human WIPI protein family of PI(3)P-binding factors and showed that WIPI-1 (Atg18) is linked to autophagy in human cells. 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) WD repeat domain, phosphoinositide interacting 1 Homo sapiens
3 WIPI-1 puncta-formation is inhibited by wortmannin and LY294002, and PI(3)P-binding-deficient WIPI-1 is puncta-formation-incompetent. 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) WD repeat domain, phosphoinositide interacting 1 Homo sapiens