Pub. Date : 2007 Aug
PMID : 17617806
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ketotifen (5-50 microM) significantly down-regulated lipopolysaccharide (LPS)-induced MDC, MIG and IP-10 (p < 0.05, each comparison) in THP-1 cells and human primary monocytes in a dose-dependent manner. | Ketotifen | C-C motif chemokine ligand 22 | Homo sapiens |
| 2 | These data demonstrate that ketotifen is effective in down-regulating LPS-induced MDC, MIG and IP-10, which play important roles in the pathogenesis of airway inflammation. | Ketotifen | C-C motif chemokine ligand 22 | Homo sapiens |