Title : TCR/CD28-stimulated actin dynamics are required for NFAT1-mediated transcription of c-rel leading to CD28 response element activation.

Pub. Date : 2007 Jul 15

PMID : 17617603






1 Functional Relationships(s)
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1 Cytochalasin D treatment impaired T cell activation by causing a reduction in TCR/CD28-mediated calcium flux, and blocked activation of two regulatory elements within the IL-2 promoter, NFAT/AP-1 and CD28RE/AP. Cytochalasin D interleukin 2 Homo sapiens