Title : Selenium activates p53 and p38 pathways and induces caspase-independent cell death in cervical cancer cells.

Pub. Date : 2008 Apr

PMID : 17610029






1 Functional Relationships(s)
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1 We conclude that selenite induces caspase-independent apoptosis in cervical carcinoma cells mostly by oxidative stress-mediated activation of p53 and p38 pathways, but other selenite-mediated effects, in particular mitochondria-specific ones, are also involved. Selenious Acid tumor protein p53 Homo sapiens