Title : Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses.

Pub. Date : 2007 Sep

PMID : 17609268






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Like TRIMCyp, Fv1-Cyp restricts HIV-1 and FIV and is sensitive to inhibition by cyclosporine. Cyclosporine peptidylprolyl isomerase G Homo sapiens
2 This notion is supported by the observation that infectivity of Fv1-Cyp restricted virus can be rescued by cyclosporine for several hours after infection, whereas virus restricted by TRIMCyp is terminally restricted after around 40 min. Cyclosporine peptidylprolyl isomerase G Homo sapiens