Title : Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice.

Pub. Date : 2007 Oct

PMID : 17604873






1 Functional Relationships(s)
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1 In the primary lung tumour model, 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), benzo(a)pyrene (BaP), urethane induces specific K-ras mutations in codon 12, codon 12, and codon 61, respectively, in the A/J mice. 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone Kirsten rat sarcoma viral oncogene homolog Mus musculus